Coeliac disease and dermatitis herpetiformis.
نویسندگان
چکیده
A national survey of 1937 members of the Canadian Celiac Association was conducted by mail questionnaire in June 1989 to study problems in diagnosing and managing celiac disease (CD) and dermatitis herpetiformis. Although 82% of the 1294 respondents were biopsied, 14% were diagnosed by their dramatic response to the gluten-free diet. Fifteen percent of biopsy-proven respondents saw five or more doctors before CD was diagnosed. Mean delays in diagnosis ranged from 5.8 (±10.9) years for those with nausea or vomiting to 13.9 (±14.5) years for those with headache or migraine.
منابع مشابه
Jejunal mucosal immunoglobulin-containing cells and jejunal fluid immunoglobulins in adult coeliac disease and dermatitis herpetiformis.
Immunoglobulin-containing plasma cell densities in the jejunal mucosa and serum and jejunal fluid immunoglobulins have been measured in patients with adult coeliac disease and dermatitis herpetiformis with and without jejunal mucosal abnormality. Studies were performed in patients before and after treatment of the jejunal lesion.Total immunofluorescent plasma cells were increased in untreated a...
متن کاملDermatitis herpetiformis in two patients with idiopathic steatorrhoea (adult coeliac disease).
Two patients who had had idiopathic steatorrhoea for several years developed typical eruptions of dermatitis herpetiformis. In each case the rash responded to treatment with dapsone.It is more usual for the rash to precede the enteropathy when the two occur together, but the association between coeliac disease and dermatitis herpetiformis is not yet clear.
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BACKGROUND AND AIMS Tissue transglutaminase (tTG) is an autoantigen in coeliac disease and the related disorder, dermatitis herpetiformis. The detection of autoantibodies directed against tTG is a highly specific marker of coeliac disease; however, it is unclear if there is a role for these autoantibodies in the disease process. The aim of this study was to investigate whether the catalytic tri...
متن کاملDifferent HLA associated gene combinations contribute to susceptibility for coeliac disease and dermatitis herpetiformis.
Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac disease there was a significant increase in the frequencies of A1, B8, DR3, DR7, and DQw2 compared with controls but no increase of DR2. In dermatitis herpetiformis there were similarly increased freque...
متن کاملAmino acid and peptide absorption in patients with coeliac disease.
A double-lumen perfusion technique has been used to study amino acid and peptide absorption in eight normal control subjects, 13 patients with untreated adult coeliac disease, and 16 patients with dermatitis herpetiformis who had varying morphological abnormalities of the small bowel. All subjects were perfused with isotonic solutions containing 10 mM glycyl-L-alanine and 10 mM glycine + 10 mM ...
متن کاملFamilial Duodenal Atresia
Anderson, C. M. (1960). Histological changes in the duodenal mucosa in coeliac disease: reversibility during treatment with a wheat gluten free diet. Archives of Disease in Childhood, 35, 419. Dyer, N. H. and Verbov, J. (1968). Malabsorption and the skin (correspondence). British Medical Journal, 4, 455. Fraser, N. G., Ferguson, A., and Murray, D. (1968). Dermatitis herpetiformis in two patient...
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ورودعنوان ژورنال:
- Pediatrie
دوره 30 5 شماره
صفحات -
تاریخ انتشار 1973